MANUFACTURING PROCESSES BACTERIAL IMMUNOTHERAPY

Bacterial immunotherapy involves an antigenic preparation capable of inducing a specific active immunity in a patient against an infectious agent. This immune response includes inducing the innate and adaptation mechanisms (cellular and humoral) of the immune system.

We have two types of bacterial immunotherapy vaccines:

  • Autovaccines: Inactivated microbial suspension from the patient’s sample.
  • Bacterial vaccines: Inactivated bacterial suspension from collection strains, determined by a specialist.

In Spain, bacterial vaccines stopped being sold in January 2018 and have been replaced by autovaccines. However, we continue to manufacture bacterial vaccines for export.

BACTERIAL VACCINE

The bacterial vaccine is a suspension of inactivated bacteria (determined by a specialist). It is administered sublingually with the aim of stimulating the activity of the immune system against bacteria that cause recurrent infections.

In Spain, they are no longer marketed in January 2018, as they have been replaced by autovaccines. However, we continue to manufacture bacterial vaccines for export.

Bacterial
culture
(plating
system)

Obtain biomass

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Chemical inactivation

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Biomass purification / cleansing

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Dosage

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Quality control

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Inactivation involves removing the reproductive or toxic capacity of an immunogen without affecting, or affecting as little as possible, its immunogenicity and specificity.

Chemical inactivation (formaldehyde), ensures the protein structure of the antigens (epitopes) and therefore, immunogenicity, is maintained.

Bacterial
vaccine
manufacture

Composition (specialist)

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Dosage

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Quality control of the finished product

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Dispatch

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